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standard β  (InvivoGen)


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    InvivoGen standard β
    Standard β, supplied by InvivoGen, used in various techniques. Bioz Stars score: 94/100, based on 31 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/%CE%B2+glucan/pm42233670-299-5-8?v=InvivoGen
    Average 94 stars, based on 31 article reviews
    standard β - by Bioz Stars, 2026-07
    94/100 stars

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    Although fks1Δ showed comparable intracellular replication rates relative to wild type within THP1 macrophages, fks2Δ mutants showed a severe attenuation of intracellular replication rates ( A ). Fks2 F659del induced a significantly lower cytotoxicity to THP1 macrophages compared to wild type ( B ). Fks2 F659del and fks1Δ mutants had the highest and lowest phagocytosis by primary human neutrophils ( C ), whereas only neutrophils infected with fks2Δ mutants produced a significantly higher ROS ( D ). Fks2 F659del and fks2Δ mutants had the lowest survival during interaction with primary human neutrophils ( E ). Cell wall exposure analysis revealed that Fks2 F659del mutants had the highest mannan exposure ( F ), Fks2 F659del , Fks2 F659V , and fks1Δ exhibited a significantly higher chitin exposure ( G ), and fks1Δ showed the least β-glucan exposure ( H ). Each data point reflects an individual biological replicate in all figures. The Wilcoxon test was used for analysis. *, **, ***, and **** refer to P values <0.05 and >0.01, <0.01, <0.005, and <0.0005, respectively. THP1: Tohoku Hospital Pediatrics-1.

    Journal: Antimicrobial Agents and Chemotherapy

    Article Title: Multidimensional assessment of in-host fitness costs of echinocandin resistance in the opportunistic fungal pathogen Candida glabrata reveals the niche-specific requirement for FKS1 and FKS2 during infection and gut colonization

    doi: 10.1128/aac.01801-25

    Figure Lengend Snippet: Although fks1Δ showed comparable intracellular replication rates relative to wild type within THP1 macrophages, fks2Δ mutants showed a severe attenuation of intracellular replication rates ( A ). Fks2 F659del induced a significantly lower cytotoxicity to THP1 macrophages compared to wild type ( B ). Fks2 F659del and fks1Δ mutants had the highest and lowest phagocytosis by primary human neutrophils ( C ), whereas only neutrophils infected with fks2Δ mutants produced a significantly higher ROS ( D ). Fks2 F659del and fks2Δ mutants had the lowest survival during interaction with primary human neutrophils ( E ). Cell wall exposure analysis revealed that Fks2 F659del mutants had the highest mannan exposure ( F ), Fks2 F659del , Fks2 F659V , and fks1Δ exhibited a significantly higher chitin exposure ( G ), and fks1Δ showed the least β-glucan exposure ( H ). Each data point reflects an individual biological replicate in all figures. The Wilcoxon test was used for analysis. *, **, ***, and **** refer to P values <0.05 and >0.01, <0.01, <0.005, and <0.0005, respectively. THP1: Tohoku Hospital Pediatrics-1.

    Article Snippet: Concanavalin A AF-647, wheat-germ agglutinin-FITC, and anti-β-glucan primary antibody (Biosupplies) were used to detect mannan, chitin, and β-glucan, respectively.

    Techniques: Infection, Produced